Discordant regulation of proteins of cholesterol metabolism during the acute phase response

Recent studies have shown that the administration of endotoxin (LPS) and cytokines to Syrian hamsters increases serum cholesterol levels, hepatic cholesterol synthesis, and the activity, protein levels, and mRNA levels of hepatic HMG-CoA reductase. Despite the greater than 10-fold increase in HMG-Co...

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Bibliographic Details
Main Authors: K R Feingold, A S Pollock, A H Moser, J K Shigenaga, C Grunfeld
Format: Article
Language:English
Published: Elsevier 1995-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520397340