Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming

Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming

<p>Abstract</p> <p>Background</p> <p>Mouse preimplantation development is characterized by both active and passive genomic demethylation. A short isoform of the prevalent maintenance DNA methyltransferase (Dnmt1S) is found in the cytoplasm of preimplantation embryos and...

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Bibliographic Details
Main Authors: Bader Michael, Alenina Natalia, Schermelleh Lothar, Spada Fabio, Grohmann Maik, Cardoso M Cristina, Leonhardt Heinrich
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/5/18

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http://www.biomedcentral.com/1471-213X/5/18

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