Differential Regulation of Interferon Signaling Pathways in CD4<sup>+</sup> T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype

Differential Regulation of Interferon Signaling Pathways in CD4<sup>+</sup> T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype

In the era of personalized medicine, insights into the molecular mechanisms that differentially contribute to disease phenotypes, such as asthma phenotypes including obesity-associated asthma, are urgently needed. Peripheral blood was drawn from 10 obese, non-atopic asthmatic adults with a high body...

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Bibliographic Details
Main Authors: Fahd Alhamdan, Leigh M. Marsh, Frauke Pedersen, Bilal Alashkar Alhamwe, Clemens Thölken, Petra Ina Pfefferle, Thomas Bahmer, Timm Greulich, Daniel P. Potaczek, Holger Garn
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
low type-2 asthma
obesity
asthma phenotypes
CD4<sup>+</sup> T cells
transcriptomics
Online Access:https://www.mdpi.com/1422-0067/22/18/10144

Internet

https://www.mdpi.com/1422-0067/22/18/10144

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