The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1.

The mechanism of PKAc-dependent NF-κB activation and subsequent translocation into the nucleus is not well defined. Previously, we showed that A kinase interacting protein 1 (AKIP1) was important for binding and retaining PKAc in the nucleus. Since then, other groups have demonstrated that AKIP1 bin...

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Bibliographic Details
Main Authors: Charles C King, Mira Sastri, Philip Chang, Juniper Pennypacker, Susan S Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3083391?pdf=render