Biphasic Regulation of Mesenchymal Genes Controls Fate Switches During Hematopoietic Differentiation of Human Pluripotent Stem Cells

Biphasic Regulation of Mesenchymal Genes Controls Fate Switches During Hematopoietic Differentiation of Human Pluripotent Stem Cells

Abstract Epithelial‐mesenchymal transition (EMT) or its reverse process mesenchymal‐epithelial transition (MET) occurs in multiple physiological and pathological processes. However, whether an entire EMT–MET process exists and the potential function during human hematopoiesis remain largely elusive....

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Bibliographic Details
Main Authors: Hongtao Wang, Mengge Wang, Yuqi Wen, Changlu Xu, Xiaoyuan Chen, Dan Wu, Pei Su, Wen Zhou, Tao Cheng, Lihong Shi, Jiaxi Zhou
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Advanced Science
Subjects:
HAND1
hematopoietic differentiation
human pluripotent stem cells
mesenchymal genes
SNAI1
Online Access:https://doi.org/10.1002/advs.202001019

Internet

https://doi.org/10.1002/advs.202001019

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