Analytical parameters and validation of homopolymer detection in a pyrosequencing-based next generation sequencing system

Analytical parameters and validation of homopolymer detection in a pyrosequencing-based next generation sequencing system

Abstract Background Current technologies in next-generation sequencing are offering high throughput reads at low costs, but still suffer from various sequencing errors. Although pyro- and ion semiconductor sequencing both have the advantage of delivering long and high quality reads, problems might o...

Full description

Bibliographic Details
Main Authors: Gergely Ivády, László Madar, Erika Dzsudzsák, Katalin Koczok, János Kappelmayer, Veronika Krulisova, Milan Macek, Attila Horváth, István Balogh
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Genomics
Subjects:
Pyrosequencing
Homopolymer detection
Cystic fibrosis
Online Access:http://link.springer.com/article/10.1186/s12864-018-4544-x

Internet

http://link.springer.com/article/10.1186/s12864-018-4544-x

Similar Items