Emerging functions of the EGFR in cancer

The physiological function of the epidermal growth factor receptor (EGFR) is to regulate epithelial tissue development and homeostasis. In pathological settings, mostly in lung and breast cancer and in glioblastoma, the EGFR is a driver of tumorigenesis. Inappropriate activation of the EGFR in cance...

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Bibliographic Details
Main Authors: Sara Sigismund, Daniele Avanzato, Letizia Lanzetti
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12155