The role of HLA-G molecule and HLA-G gene polymorphisms in tumors, viral hepatitis and parasitic diseases

The role of HLA-G molecule and HLA-G gene polymorphisms in tumors, viral hepatitis and parasitic diseases

Considering that the non-classical HLA-G molecule has well-recognized tolerogenic properties, HLA-G expression is expected to be deleterious when present in tumor cells and in cells chronically infected by viruses, whereas HLA-G expression is expected to be advantageous in autoimmune disorders. The...

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Bibliographic Details
Main Authors: Fabrício César Dias, Erick C. Castelli, Cristhianna Viesti Advincula Collares, Philippe eMoreau, Eduardo Antonio Donadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
tumors
polymorphism
Viral Hepatitis
HLA-G
Parasitic disorders
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00009/full

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