Deregulated Expression of the Human Tumor Marker CEA and CEA Family Member CEACAM6 Disrupts Tissue Architecture and Blocks Colonocyte Differentiation

Deregulated Expression of the Human Tumor Marker CEA and CEA Family Member CEACAM6 Disrupts Tissue Architecture and Blocks Colonocyte Differentiation

Human carcinoembryonic antigen (CEA) and the CEA family member CEACAM6 (formerly nonspecific crossreacting antigen [NCA]) function in vitro, at least, as homotypic intercellular adhesion molecules and, in model systems, can block the terminal differentiation and anoikis of several different cell ty...

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Bibliographic Details
Main Authors: Christian Ilantzis, Luisa Demarte, Robert A. Screaton, Clifford P. Stanners
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
carcinoembryonic antigen
colon cancer
tissue architecture
colonocyte differentation
cell polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558602800082

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http://www.sciencedirect.com/science/article/pii/S1476558602800082

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