Immunopathogenesis of Pediatric Localized Scleroderma

Immunopathogenesis of Pediatric Localized Scleroderma

Localized scleroderma (LS) is a complex disease characterized by a mixture of inflammation and fibrosis of the skin that, especially in the pediatric population, also affects extracutaneous tissues ranging from muscle to the central nervous system. Although developmental origins have been hypothesiz...

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Bibliographic Details
Main Authors: Kathryn S. Torok, Suzanne C. Li, Heidi M. Jacobe, Sarah F. Taber, Anne M. Stevens, Francesco Zulian, Theresa T. Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
localized scleroderma
morphea
pediatric rheumatology
immunophenotype
disease etiology
autoimmune disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00908/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00908/full

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