Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles.

Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles.

Recombinant subunit vaccine engineering increasingly focuses on the development of more effective delivery platforms. However, current recombinant vaccines fail to sufficiently stimulate protective adaptive immunity against a wide range of pathogens while remaining a cost effective solution to globa...

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Bibliographic Details
Main Authors: Joseph A Rosenthal, Chung-Jr Huang, Anne M Doody, Tiffany Leung, Kaho Mineta, Danielle D Feng, Elizabeth C Wayne, Nozomi Nishimura, Cynthia Leifer, Matthew P DeLisa, Susana Mendez, David Putnam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4245113?pdf=render

Internet

http://europepmc.org/articles/PMC4245113?pdf=render

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