Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells

Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells

Licochalcone A (LCA) is a chalcone that is predominantly found in the root of <i>Glycyrrhiza</i> species, which is widely used as an herbal medicine. Although previous studies have reported that LCA has a wide range of pharmacological effects, evidence for the underlying molecular mechan...

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Bibliographic Details
Main Authors: Su Hyun Hong, Hee-Jae Cha, Hyun Hwang-Bo, Min Yeong Kim, So Young Kim, Seon Yeong Ji, JaeHun Cheong, Cheol Park, Hyesook Lee, Gi-Young Kim, Sung-Kwon Moon, Seok Joong Yun, Young-Chae Chang, Wun-Jae Kim, Yung Hyun Choi
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
Licochalcone A
bladder cancer
G2/M arrest
apoptosis
ROS
Online Access:https://www.mdpi.com/1422-0067/20/15/3820

Internet

https://www.mdpi.com/1422-0067/20/15/3820

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