A multivalent T-antigen-based vaccine for Group A Streptococcus

A multivalent T-antigen-based vaccine for Group A Streptococcus

Abstract Pili of Group A Streptococcus (GAS) are surface-exposed structures involved in adhesion and colonisation of the host during infection. The major protein component of the GAS pilus is the T-antigen, which multimerises to form the pilus shaft. There are currently no licenced vaccines against...

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Bibliographic Details
Main Authors: Jacelyn M. S. Loh, Tania Rivera-Hernandez, Reuben McGregor, Adrina Hema J. Khemlani, Mei Lin Tay, Amanda J. Cork, Jeremy M. Raynes, Nicole J. Moreland, Mark J. Walker, Thomas Proft
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83673-4

Internet

https://doi.org/10.1038/s41598-021-83673-4

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