A multi-sample approach increases the accuracy of transcript assembly

Transcript assembly is an important step in analysis of RNA-seq data whose accuracy influences downstream quantification, detection and characterization of alternative splice variants. Here, the authors develop PsiCLASS, a transcript assembler leveraging simultaneous analysis of multiple RNA-seq sam...

Full description

Bibliographic Details
Main Authors: Li Song, Sarven Sabunciyan, Guangyu Yang, Liliana Florea
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12990-0