Factors targeting MED12 to drive tumorigenesis? [version 2; referees: 2 approved, 1 approved with reservations]
Mediator Complex Subunit 12 (MED12) is part of the transcriptional preinitiation machinery. Mutations of its gene predominantly occur in two types of highly frequent benign tumors, uterine leiomyomas and fibroadenomas of the breast, where they apparently act as driver mutations. Nevertheless, their...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2018-12-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/7-359/v2 |