Potent and selective antiplasmodial activity of marine sponges from Bahia state, Brazil

Potent and selective antiplasmodial activity of marine sponges from Bahia state, Brazil

This study evaluated the in vitro antiplasmodial and cytotoxic effects of 26 extracts from nine marine sponges collected in Salvador, Bahia state, Brazil. All assayed extracts were found to be potently active against Plasmodium falciparum W2 strain, with IC50 values ranging from 0.28 to 22.34 μg mL−...

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Bibliographic Details
Main Authors: Uesley Vieira Alves, Eujeane Jardim e Silva, Jailciele Gonzaga dos Santos, Luisa Oliveira Santos, Emilio Lanna, Ana Claudia de Souza Pinto, Amanda Luisa da Fonseca, Fernando de Pilla Varotti, Ronan Batista
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Marine sponges
Plasmodium falciparum
Malaria
Selective antiplasmodial activity
Chloroquine-resistant W2 strain
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320721000385

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http://www.sciencedirect.com/science/article/pii/S2211320721000385

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