Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection.

The intestine is a common site for a variety of pathogenic infections. Helminth infections continue to be major causes of disease worldwide, and are a significant burden on health care systems. Lysine methyltransferases are part of a family of novel attractive targets for drug discovery. SETD7 is a...

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Bibliographic Details
Main Authors: Menno J Oudhoff, Frann Antignano, Alistair L Chenery, Kyle Burrows, Stephen A Redpath, Mitchell J Braam, Georgia Perona-Wright, Colby Zaph
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005876