Modeling the dynamics and kinetics of HIV-1 Gag during viral assembly.

We report a computational model for the assembly of HIV-1 Gag into immature viral particles at the plasma membrane. To reproduce experimental structural and kinetic properties of assembly, a process occurring on the order of minutes, a coarse-grained representation consisting of a single particle pe...

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Bibliographic Details
Main Authors: Michael D Tomasini, Daniel S Johnson, Joshua S Mincer, Sanford M Simon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5909904?pdf=render