Insulin receptor isoforms A and B as well as insulin receptor substrates-1 and -2 are differentially expressed in prostate cancer.

AIMS/HYPOTHESIS: In different cancers types, insulin receptor isoform composition or insulin receptor substrate (IRS) isoforms are different to healthy tissue. This may be a molecular link to increased cancer risk in diabetes and obesity. Since this is yet unclear for prostate cancer, we investigate...

Full description

Bibliographic Details
Main Authors: Martin Heni, Jörg Hennenlotter, Marcus Scharpf, Stefan Z Lutz, Christian Schwentner, Tilman Todenhöfer, David Schilling, Ursula Kühs, Valentina Gerber, Fausto Machicao, Harald Staiger, Hans-Ulrich Häring, Arnulf Stenzl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519512?pdf=render