Selective Serotonin Reuptake Inhibitor Pharmaco-Omics: Mechanisms and Prediction

Selective serotonin reuptake inhibitors (SSRIs) are a standard of care for the pharmacotherapy of patients suffering from Major Depressive Disorder (MDD). However, only one-half to two-thirds of MDD patients respond to SSRI therapy. Recently, a “multiple omics” research strategy was applied to ident...

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Bibliographic Details
Main Authors: Thanh Thanh L. Nguyen, Duan Liu, Ming-Fen Ho, Arjun P. Athreya, Richard Weinshilboum
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.614048/full