Dkk1: A key molecule in joint remodelling and fibrosis

Dickkopf-1 (Dkk-1) is a Wnt signaling pathway inhibitor that has been shown to play an important role in joint remodeling, in experimental models of arthritis and in humans. Recent data suggest that this molecule is involved in the fibrotic process as well. OBJECTIVES: This review summarizes all the...

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Bibliographic Details
Main Authors: Kalliopi Klavdianou, Stamatis-Nick Liossis, Dimitrios Daoussis
Format: Article
Language:English
Published: PCO Convin S.A. 2017-01-01
Series:Mediterranean Journal of Rheumatology
Subjects:
Online Access:https://www.mjrheum.org/assets/files/792/file99_885.pdf