Advances in neural organoid systems and their application in neurotoxicity testing of environmental chemicals

Abstract Due to the complex structure and function of central nervous system (CNS), human CNS in vitro modeling is still a great challenge. Neurotoxicity testing of environmental chemicals mainly depends on the traditional animal models, which have various limitations such as species differences, ex...

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Bibliographic Details
Main Authors: Yuanyuan Zheng, Fangrong Zhang, Shengmin Xu, Lijun Wu
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genes and Environment
Subjects:
CNS
Online Access:https://doi.org/10.1186/s41021-021-00214-1