Personalized pathway enrichment map of putative cancer genes from next generation sequencing data.

BACKGROUND: Pathway analysis of a set of genes represents an important area in large-scale omic data analysis. However, the application of traditional pathway enrichment methods to next-generation sequencing (NGS) data is prone to several potential biases, including genomic/genetic factors (e.g., th...

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Bibliographic Details
Main Authors: Peilin Jia, Zhongming Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3356304?pdf=render