Promiscuity progression of bioactive compounds over time [v1; ref status: indexed, http://f1000r.es/5cx]

In the context of polypharmacology, compound promiscuity is rationalized as the ability of small molecules to specifically interact with multiple targets. To study promiscuity progression of bioactive compounds in detail, nearly 1 million compounds and more than 5.2 million activity records were ana...

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Bibliographic Details
Main Authors: Ye Hu, Swarit Jasial, Jürgen Bajorath
Format: Article
Language:English
Published: F1000 Research Ltd 2015-05-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-118/v1