Two-Step Size-Exclusion Nanofiltration of Prothrombin Complex Concentrate Using Nanocellulose-Based Filter Paper

Two-Step Size-Exclusion Nanofiltration of Prothrombin Complex Concentrate Using Nanocellulose-Based Filter Paper

<b> </b>Coagulation Factor IX-rich protrhombin complex concentrate (FIX-PCC) is a therapeutic biologic product that consists of a mixture of several human plasma-derived proteins, useful for treating hemophilia B. Due to its complex composition, FIX-PCC is very challenging to bioprocess...

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Bibliographic Details
Main Authors: Levon Manukyan, Athanasios Mantas, Mikhail Razumikhin, Andrey Katalevsky, Eugen Golubev, Albert Mihranyan
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomedicines
Subjects:
mille-feuille filter
cladophora cellulose
hemophilia b
protein aggregates
virus removal filtration
Online Access:https://www.mdpi.com/2227-9059/8/4/69

Internet

https://www.mdpi.com/2227-9059/8/4/69

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