Identification of Copy Number Aberrations in Breast Cancer Subtypes Using Persistence Topology
DNA copy number aberrations (CNAs) are of biological and medical interest because they help identify regulatory mechanisms underlying tumor initiation and evolution. Identification of tumor-driving CNAs (driver CNAs) however remains a challenging task, because they are frequently hidden by CNAs that...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2015-08-01
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| Series: | Microarrays |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3905/4/3/339 |