CR4 Signaling Contributes to a DC-Driven Enhanced Immune Response Against Complement-Opsonized HIV-1

CR4 Signaling Contributes to a DC-Driven Enhanced Immune Response Against Complement-Opsonized HIV-1

Dendritic cells (DCs) possess intrinsic cellular defense mechanisms to specifically inhibit HIV-1 replication. In turn, HIV-1 has evolved strategies to evade innate immune sensing by DCs resulting in suboptimal maturation and poor antiviral immune responses. We previously showed that complement-opso...

Full description

Bibliographic Details
Main Authors: Marta Bermejo-Jambrina, Michael Blatzer, Paula Jauregui-Onieva, Teodor E. Yordanov, Paul Hörtnagl, Taras Valovka, Lukas A. Huber, Doris Wilflingseder, Wilfried Posch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
HIV-1
dendritic cell
complement
CD11c
CD11b
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02010/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02010/full

Similar Items