Theiler's murine encephalomyelitis virus as a vaccine candidate for immunotherapy.

The induction of sterilizing T-cell responses to tumors is a major goal in the development of T-cell vaccines for treating cancer. Although specific components of anti-viral CD8+ immunity are well characterized, we still lack the ability to mimic viral CD8+ T-cell responses in therapeutic settings f...

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Bibliographic Details
Main Authors: Kevin D Pavelko, Megan A Girtman, Yoshihiro Mitsunaga, Yanice V Mendez-Fernandez, Michael P Bell, Michael J Hansen, Kathleen S Allen, Moses Rodriguez, Larry R Pease
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3098865?pdf=render