Novel Mutations in PSENEN Gene in Two Chinese Acne Inversa Families Manifested as Familial Multiple Comedones and Dowling-Degos Disease

Novel Mutations in PSENEN Gene in Two Chinese Acne Inversa Families Manifested as Familial Multiple Comedones and Dowling-Degos Disease

Background: Acne inversa (AI), also called hidradenitis suppurativa, is a chronic, inflammatory, recurrent skin disease of the hair follicle. Familial AI shows autosomal-dominant inheritance caused by mutations in the γ-secretase genes. This study was aimed to identify the specific mutations in the...

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Bibliographic Details
Main Authors: Cheng Zhou, Guang-Dong Wen, Lwin Myint Soe, Hong-Jun Xu, Juan Du, Jian-Zhong Zhang
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Acne Inversa; Comedones; Dowling-Degos Disease; Hidradenitis Suppurativa; PSENEN; Squamous Cell Carcinoma
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=23;spage=2834;epage=2839;aulast=Zhou

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=23;spage=2834;epage=2839;aulast=Zhou

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