Environmental cadmium exposure induces fetal growth restriction via triggering PERK-regulated mitophagy in placental trophoblasts

Environmental cadmium exposure induces fetal growth restriction via triggering PERK-regulated mitophagy in placental trophoblasts

Cadmium (Cd), an environmental toxicant, is positively associated with fetal growth restriction (FGR). However, the mechanism by which gestational exposure to Cd induces FGR remains unclear. This study designed in vitro and in vivo experiments to explore the role of placental mitophagy in Cd-impaire...

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Bibliographic Details
Main Authors: Hua-Long Zhu, Xue-Ting Shi, Xiao-Feng Xu, Yong-Wei Xiong, Song-Jia Yi, Guo-Xiang Zhou, Wei-Bo Liu, Miao-Miao Huang, Lan Gao, Cheng Zhang, Ling-Li Zhao, De-Xiang Xu, Hua Wang
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Environment International
Subjects:
Environmental cadmium
Fetal growth restriction
Placenta
Mitophagy
PERK
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412020322741

Internet

http://www.sciencedirect.com/science/article/pii/S0160412020322741

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