Computational Drug Design Applied to the Study of Metabotropic Glutamate Receptors

Metabotropic glutamate (mGlu) receptors are a family of eight GPCRs that are attractive drug discovery targets to modulate glutamate action and response. Here we review the application of computational methods to the study of this family of receptors. X-ray structures of the extracellular and 7-tran...

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Bibliographic Details
Main Authors: Claudia Llinas del Torrent, Laura Pérez-Benito, Gary Tresadern
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/6/1098