Genomic Insertion of a Heterologous Acetyltransferase Generates a New Lipopolysaccharide Antigenic Structure in Brucella abortus and Brucella melitensis

Genomic Insertion of a Heterologous Acetyltransferase Generates a New Lipopolysaccharide Antigenic Structure in Brucella abortus and Brucella melitensis

Brucellosis is a bacterial zoonosis of worldwide distribution caused by bacteria of the genus Brucella. In Brucella abortus and Brucella melitensis, the major species infecting domestic ruminants, the smooth lipopolysaccharide (S-LPS) is a virulence factor. This S-LPS carries a N-formyl-perosamine h...

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Bibliographic Details
Main Authors: Estrella Martínez-Gómez, Jonas Ståhle, Yolanda Gil-Ramírez, Amaia Zúñiga-Ripa, Mona Zaccheus, Ignacio Moriyón, Maite Iriarte, Göran Widmalm, Raquel Conde-Álvarez
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Subjects:
lipopolysaccharide (LPS)
bacterial pathogenesis
bacteria
vaccine development
virulence factor
antigen
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01092/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01092/full

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