Elderly subjects have a delayed antibody response and prolonged viraemia following yellow fever vaccination: a prospective controlled cohort study.

BACKGROUND: Yellow fever vaccination (YF-17D) can cause serious adverse events (SAEs). The mechanism of these SAEs is poorly understood. Older age has been identified as a risk factor. We tested the hypothesis that the humoral immune response to yellow fever vaccine develops more slowly in elderly t...

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Bibliographic Details
Main Authors: Anna H Roukens, Darius Soonawala, Simone A Joosten, Adriëtte W de Visser, Xiaohong Jiang, Kees Dirksen, Marjolein de Gruijter, Jaap T van Dissel, Peter J Bredenbeek, Leo G Visser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3233541?pdf=render