Germline Risk Contribution to Genomic Instability in Multiple Myeloma

Genomic instability, a well-established hallmark of human cancer, is also a driving force in the natural history of multiple myeloma (MM) – a difficult to treat and in most cases fatal neoplasm of immunoglobulin producing plasma cells that reside in the hematopoietic bone marrow. Long recognized man...

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Bibliographic Details
Main Authors: Siegfried Janz, Fenghuang Zhan, Fumou Sun, Yan Cheng, Michael Pisano, Ye Yang, Hartmut Goldschmidt, Parameswaran Hari
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00424/full