Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate levels.

Bibliographic Details
Main Authors: Bonnie R. Joubert, Herman T. den Dekker, Janine F. Felix, Jon Bohlin, Symen Ligthart, Emma Beckett, Henning Tiemeier, Joyce B. van Meurs, Andre G. Uitterlinden, Albert Hofman, Siri E. Håberg, Sarah E. Reese, Marjolein J. Peters, Bettina Kulle Andreassen, Eric A. P. Steegers, Roy M. Nilsen, Stein E. Vollset, Øivind Midttun, Per M. Ueland, Oscar H. Franco, Abbas Dehghan, Johan C. de Jongste, Michael C. Wu, Tianyuan Wang, Shyamal D. Peddada, Vincent W. V. Jaddoe, Wenche Nystad, Liesbeth Duijts, Stephanie J. London
Format: Article
Language:English
Published: Nature Publishing Group 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10577

Internet

https://doi.org/10.1038/ncomms10577

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