Distinguishing Latent from Active Mycobacterium tuberculosis Infection Using Elispot Assays: Looking Beyond Interferon-gamma

Distinguishing Latent from Active Mycobacterium tuberculosis Infection Using Elispot Assays: Looking Beyond Interferon-gamma

Mycobacterium tuberculosis (MTB) is a global heath epidemic, its threat amplified by HIV infection and the emergence of multidrug-resistant tuberculosis (MDR-TB). Interferon (IFN)-gamma release assays (IGRAs) have improved the accuracy of detection of MTB exposure in some subject groups as compared...

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Bibliographic Details
Main Authors: Jennifer E. Snyder-Cappione, Amedeo J. Cappione III, Camilla Tincati
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Cells
Subjects:
mycobacterium tuberculosis
Elispot
polyfunctional T cell
IFN-gamma
LTBI
active MTB
Online Access:http://www.mdpi.com/2073-4409/1/2/89

Internet

http://www.mdpi.com/2073-4409/1/2/89

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