Administration of cardiac mesenchymal cells modulates innate immunity in the acute phase of myocardial infarction in mice
Abstract Although cardiac mesenchymal cell (CMC) therapy mitigates post-infarct cardiac dysfunction, the underlying mechanisms remain unidentified. It is acknowledged that donor cells are neither appreciably retained nor meaningfully contribute to tissue regeneration—suggesting a paracrine-mediated...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-09-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-71580-z |