Receptor oligomerization: from early evidence to current understanding in class B GPCRs

Receptor oligomerization: from early evidence to current understanding in class B GPCRs

Dimerization or oligomerization of G protein-coupled receptors (GPCRs) are known to modulate receptor functions in terms of ontogeny, ligand-oriented regulation, pharmacological diversity, signal transduction and internalization. Class B GPCRs are receptors to a family of hormones including secretin...

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Bibliographic Details
Main Authors: Stephanie Yuen Lam Ng, Leo Tsz On Lee, Billy Kwok Chong Chow
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Endocrinology
Subjects:
Oligomerization
BRET
GPCR
class B1
secretin receptor
class B
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00175/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00175/full

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