Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models

Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models

Rabies, a fatal disease in humans and other mammals, is caused by the rabies virus (RABV), and it poses a public health threat in many parts of the world. Once symptoms of rabies appear, the mortality is near 100%. There is currently no effective treatment for rabies. In our study, two human-derived...

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Bibliographic Details
Main Authors: Fei Huang, Meishen Ren, Jie Pei, Hong Mei, Baokun Sui, Qiong Wu, Benjie Chai, Ruicheng Yang, Ming Zhou, Zhen F. Fu, Huiping Zhou, Ling Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
rabies viruses
adeno-associated virus
virus-neutralizing antibody
preexposure prophylaxis
postexposure prophylaxis
rodent models
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.702273/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.702273/full

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