Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury

Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury

Recent studies suggested that sestrin2 is a crucial modulator for the production of reactive oxygen species (ROS). In addition, sestrin2 may also regulate ribosomal protein S6 (RpS6), a molecule important for protein synthesis, through the effect of mammalian target of rapamycin (mTOR) complex that...

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Bibliographic Details
Main Authors: Yao-Chung Chuang, Jenq-Lin Yang, Ding-I Yang, Tsu-Kung Lin, Chia-Wei Liou, Shang-Der Chen
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
transient global ischemia
hippocampus CA1 neurons
oxidative stress
ribosomal protein S6
sestrin2
Online Access:http://www.mdpi.com/1422-0067/16/11/25963

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http://www.mdpi.com/1422-0067/16/11/25963

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