Pharmacological Potential of Endothelin Receptors Agonists and Antagonists
Endothelins are potent predominantly vasoconstricting agents that act as local autocrine and paracrine mediators. Endothelin-1 is the most potent and sustained vasoconstrictor and pressor substance yet identified. Abnormalities of the endothelin system occur in a range of diseases associated with va...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karolinum Press
2005-01-01
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| Series: | Acta Medica |
| Subjects: | |
| Online Access: | https://actamedica.lfhk.cuni.cz/48/2/0067/ |