Protein engineering of Saccharomyces cerevisiae transporter Pdr5p identifies key residues that impact Fusarium mycotoxin export and resistance to inhibition

Protein engineering of Saccharomyces cerevisiae transporter Pdr5p identifies key residues that impact Fusarium mycotoxin export and resistance to inhibition

Abstract Cereal infection by the broad host range fungal pathogen Fusarium graminearum is a significant global agricultural and food safety issue due to the deposition of mycotoxins within infected grains. Methods to study the intracellular effects of mycotoxins often use the baker's yeast mode...

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Bibliographic Details
Main Authors: Amanda B. Gunter, Anne Hermans, Whynn Bosnich, Douglas A. Johnson, Linda J. Harris, Steve Gleddie
Format: Article
Language:English
Published: Wiley 2016-12-01
Series:MicrobiologyOpen
Subjects:
ABC transporters
deoxynivalenol
drug resistance
enniatin
Fusarium graminearum
yeast
Online Access:https://doi.org/10.1002/mbo3.381

Internet

https://doi.org/10.1002/mbo3.381

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