MYC Immunohistochemistry Predicts MYC Rearrangements by FISH

MYC is the proto-oncogene classically associated with Burkitt lymphoma (BL) located at chromosomal locus 8q24. Rearrangements of MYC are seen in nearly 100% of BL but have been reported in 3–16% of diffuse large B-cell lymphomas (DLBCLs). Rearrangements of MYC are tested for by flourescence in situ...

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Bibliographic Details
Main Authors: Julum Nwanze, Momin T. Siddiqui, Keith A. Stevens, Debra Saxe, Cynthia Cohen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Oncology
Subjects:
MYC
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00209/full