miR451 and AMPK mutual antagonism in glioma cell migration and proliferation: a mathematical model.

Glioblastoma multiforme (GBM) is the most common and the most aggressive type of brain cancer; the median survival time from the time of diagnosis is approximately one year. GBM is characterized by the hallmarks of rapid proliferation and aggressive invasion. miR-451 is known to play a key role in g...

Full description

Bibliographic Details
Main Authors: Yangjin Kim, Soyeon Roh, Sean Lawler, Avner Friedman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3243681?pdf=render