Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease PatientsSummary

Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease PatientsSummary

Background & Aims: Substance P (SP) neurokinin-1 receptors (NK-1Rs) are expressed in mesenteric preadipocytes, and SP binding activates proinflammatory signaling in these cells. We evaluated the expression levels of SP (Tac-1), NK-1R (Tacr-1), and NK-2R (Tacr-2) mRNA in preadipocytes isolated fr...

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Bibliographic Details
Main Authors: Aristea Sideri, Kyriaki Bakirtzi, David Q. Shih, Hon Wai Koon, Phillip Fleshner, Razvan Arsenescu, Violeta Arsenescu, Jerrold R. Turner, Iordanes Karagiannides, Charalabos Pothoulakis
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15000594

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http://www.sciencedirect.com/science/article/pii/S2352345X15000594

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