IFITMs from Mycobacteria Confer Resistance to Influenza Virus When Expressed in Human Cells

IFITMs from Mycobacteria Confer Resistance to Influenza Virus When Expressed in Human Cells

Interferon induced transmembrane proteins (IFITMs) found in vertebrates restrict infections by specific viruses. IFITM3 is known to be essential for restriction of influenza virus infections in both mice and humans. Vertebrate IFITMs are hypothesized to have derived from a horizontal gene transfer f...

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Bibliographic Details
Main Authors: William J. Melvin, Temet M. McMichael, Nicholas M. Chesarino, Jocelyn C. Hach, Jacob S. Yount
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Viruses
Subjects:
interferon induced transmembrane protein
IFITM3
influenza virus
virus restriction
palmitoylation
Online Access:http://www.mdpi.com/1999-4915/7/6/2759

Internet

http://www.mdpi.com/1999-4915/7/6/2759

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