Developing highER-throughput zebrafish screens for in-vivo CNS drug discovery

The high prevalence of brain disorders and the lack of their efficient treatments necessitate improved in-vivo pre-clinical models and tests. The zebrafish (Danio rerio), a vertebrate species with high genetic and physiological homology to humans, is an excellent organism for innovative CNS drug dis...

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Bibliographic Details
Main Authors: Adam Michael Stewart, Robert eGerlai, Allan V Kalueff
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00014/full