MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation

Abstract Thioredoxin reductase 1 (TrxR1) is a selenocysteine-containing protein involved in cellular redox homeostasis which is downregulated in skeletal muscle differentiation. Here we show that TrxR1 decrease occurring during myogenesis is functionally involved in the coordination of this cellular...

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Bibliographic Details
Main Authors: Neri Mercatelli, Simona Fittipaldi, Elisa De Paola, Ivan Dimauro, Maria Paola Paronetto, Malcolm J. Jackson, Daniela Caporossi
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07575-0