Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML

The concept of leukemic stem cells (LSC) has been developed with the idea to explain the clonal hierarchies and architectures in leukemia, and the more or less curative anti-neoplastic effects of various targeted drugs. It is now widely accepted that curative therapies must have the potential to eli...

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Bibliographic Details
Main Authors: Peter Valent, Irina Sadovnik, Gregor Eisenwort, Karin Bauer, Harald Herrmann, Karoline V. Gleixner, Axel Schulenburg, Werner Rabitsch, Wolfgang R. Sperr, Dominik Wolf
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
AML
CML
leukemic stem cells
CAR-T cell therapy
bispecific antibodies
precision medicine
Online Access:https://www.mdpi.com/1422-0067/20/17/4233

Internet

https://www.mdpi.com/1422-0067/20/17/4233

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