Slow viral propagation during initial phase of infection leads to viral persistence in mice

Slow viral propagation during initial phase of infection leads to viral persistence in mice

Using different strains of the lymphocytic choriomeningitis virus (LCMV), Xu, Wang et al. show that a slow viral propagation limits type I interferon (IFN-I) production and viral persistence in mice. This study suggests a reduced viral propagation as a mechanism for immune evasion and viral persiste...

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Bibliographic Details
Main Authors: Haifeng C. Xu, Ruifeng Wang, Prashant V. Shinde, Lara Walotka, Anfei Huang, Gereon Poschmann, Jun Huang, Wei Liu, Kai Stühler, Heiner Schaal, Andreas Bergthaler, Aleksandra A. Pandyra, Cornelia Hardt, Karl S. Lang, Philipp A. Lang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02028-x

Internet

https://doi.org/10.1038/s42003-021-02028-x

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